Chronic Fatigue

Supporting Energy Production, Recovery, and Daily Functioning.

How HBOT Supports Chronic Fatigue

Chronic fatigue can place a significant strain on the body and impact daily function, energy levels, and overall wellbeing. Factors such as reduced cellular energy production, inflammation, and impaired oxygen delivery to tissues may contribute to persistent fatigue and slower recovery.

Hyperbaric Oxygen Therapy (HBOT) is a clinically recognised supportive therapy that increases the amount of oxygen delivered to the body’s tissues. By enhancing oxygen availability at a cellular level, HBOT may help support energy production, neurological function, and the body’s natural recovery processes.

HBOT is used internationally in hospital and outpatient settings to support conditions where oxygen delivery and cellular function may be compromised.

HBOT may support several key physiological processes:

  • Improved cellular energy production

  • Enhanced oxygen delivery to tissues

  • Reduced systemic inflammation

  • Support for neurological and cognitive function

  • Improved circulation and tissue oxygenation

  • Support for overall recovery and resilience

The result? Better energy, improved resilience, and support for day-to-day functioning.

Key Recovery Benefits

  • Geometric drawing of an outline square with sections divided by vertical, horizontal, and diagonal lines.

    Improved Cellular Energy Production

    HBOT increases oxygen delivery to tissues, supporting mitochondrial energy production

    A clinical study reported significant improvements in fatigue severity and quality-of-life scores after 15 HBOT sessions in patients with chronic fatigue

    Increased oxygen availability may help support overall metabolic and cellular function

  • Geometric drawing of an outline square with sections divided by vertical, horizontal, and half circle lines.

    Enhanced Cognitive Function and Mental Clarity

    Enhanced oxygen delivery to the brain may support neurological function

    Studies in fatigue-related conditions show improvements in cognitive symptoms, concentration, and brain fog following HBOT treatment

    Neuroimaging research has demonstrated measurable improvements in brain activity and neuroplasticity

  • Geometric drawing of an outline square with sections divided by vertical, horizontal, and circle lines.

    Reduced Inflammation and Improved Recovery

    HBOT has been shown to reduce inflammatory markers and oxidative stress linked to fatigue

    Studies report improvements in sleep quality, fatigue severity, and overall wellbeing after treatment

    Enhanced circulation and tissue oxygenation may support systemic recovery and resilience

  • https://pubmed.ncbi.nlm.nih.gov/23682549/

    A clinical study involving patients with Chronic Fatigue Syndrome found that 15 HBOT sessions over three weeks significantly improved fatigue severity and quality-of-life scores. Researchers concluded HBOT may help reduce symptom burden and improve daily functioning in CFS patients.

  • https://www.medrxiv.org/content/10.1101/2025.10.29.25339096v1.full.pdf

    Research involving ME/CFS patients undergoing 40 HBOT sessions reported improvements in fatigue, physical capacity, cognitive function, and muscle strength. Imaging results also suggested improvements in brain connectivity associated with fatigue symptoms.

  • https://pubmed.ncbi.nlm.nih.gov/24343585/

    Clinical trials on acute surgical and traumatic wounds (e.g., skin grafts and crush injuries) suggest HBOT may increase graft survival and reduce tissue necrosis compared to standard care, although larger, high-quality studies are still needed.

  • https://clinicaltrials.gov/ct2/show/NCT00484523

    A clinical case study reported that 50 HBOT sessions led to improvements in fatigue and cognitive symptoms, alongside normalization of abnormal brain metabolism on PET imaging.

What the research says.

Typical Chronic Fatigue Protocols

Initial HBOT Course
10–20 sessions delivered over several weeks to help increase oxygen availability at a cellular level and support the body’s energy production, circulation, and recovery processes.

Ongoing Support
Additional sessions may be recommended depending on symptom severity and individual response. Treatments are typically delivered regularly to support sustained improvements in energy levels, cognitive function, and overall wellbeing.

HBOT is provided as a supportive therapy and is tailored to each individual. It complements existing medical care and does not replace advice or treatment from a patient’s healthcare provider.

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What our clients think…

  • "The chamber was very comfortable and really helped my recovery post ultra marathon."

    — Kai O, Oxyplus Client

  • "We’re so fortunate to have this facility in Newcastle, personally I’ve benefited greatly from using the chamber for post surgery rehab and I now use it for regular maintenance."

    — Mark D, Oxyplus Client

  • "I had no idea what to expect when I attended my first appointment for oxygen therapy. I have to say that I was not disappointed!! I felt invigorated after the 30 minute session and I now book regular appointments."

    — Ruth T, Oxyplus Client

  • "After several sessions, I can confidently say that I have felt the wellness benefits. It has also helped speed up my son's recovery from knee surgery and reduced his pain."

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  • "As a professional MMA fighter I have used the oxygen chamber to recover from hard training, heal faster from injuries, and is also beneficial for head trauma and concussion which is huge for combat sports."

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